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    原著論文(年代順)

1. "Active immunization alters the plasma nicotine concentration in rats"
    The Journal of Pharmacology and Experimental Therapeutics, 283: 1076-1081 (1997)
2. "Immunization of rats reduces nicotine distribution to brain"
    Psychopharmacology, 143: 150-157 (1999)
3. " Altered disposition of repeated nicotine doses in rats immunized against nicotine"
    Nicotine & Tobacco Research, 1: 241-249 (1999)
4. "A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates
    its behavioral and cardiovascular effects in rats"
    Pharmacology Biochemistry and Behavior, 65: 191-198 (1999)
5. "Vaccination against nicotine during continued nicotine administration in rats
    :Immunogenicity of the vaccine and effects on nicotine distribution to brain"
    Int. J. Immunopharmacology, 22: 809-819 (2000)
6. "Passive immunization against nicotine prevents nicotine alleviation of nicotine     
    abstinence syndrome." 
    Pharmacology Biochemistry and Behavior, 68: 87-92 (2001)
7. "Inhibition of nicotine-induced seizures in rats by combining vaccination 
    against nicotine with chronic nicotine infusion"
    Experimental and Clinical Psychopharmacology, 9: 228-234 (2001)
8. "Passive immunization against nicotine attenuates nicotine discrimination."
    Life Science, 70: 2793-2798 (2002)
9. "Maternal vaccination against nicotine reduces nicotine distribution to 
    fetal brain in rats."
    The Journal of Pharmacology and Experimental Therapeutics, 305: 587-592 (2003)
10. "Tissue-dependent effects of immunization with a nicotine conjugate vaccine on the 
    distribution of nicotine in rats"
    Int Immunopharmacol, 3: 957-970 (2003)
11. "Reduced nicotine distribution from mother to fetal brain in rats vaccinated against"
    nicotine: time course and influence of nicotine dosing resimen""
    Biochem Pharmacol, 69: 1385-1395 (2005)
12. "Monoclonal nicotine-specific antibodies reduce nicotine distribution to brain in rats:"
    dose- and affinity-response relationships."
    Drug Metab Dispos, 33: 1056-1061 (2005)
13. "Effects of a nicotine conjugate vaccine on the acquisition and maintenance of nicotine"
    self-administration in rats."
    Psychopharmacol (in press) 2005

    News release from National Institute of Drug Abuse (NIDA)

"Nicotine Vaccine Shows Promise For Combating Tobacco Addiction" December 17, 1999
"Nicotine Vaccine Moves Toward Clinical Trials" October 2000

    新聞その他記事(抜粋)

1. "Tests promising for Minneapolis researchers' nicotine vaccine"  StarTribune, Dec.17,1999
2. "Researchers Test Nicotine Vaccine" in Washinton AP, Dec. 18, 1999
3. "Nicotine Vaccine Data for Nabi-NicVAX" in Peer Review Journal, Dec. 17, 1999
4. "Florida company develops possible nicotine vaccine", Dec, 17, 1999
5. "A tobacco vaccine in rats lowers blood levels of nicotine" ABC News, Aug, 2000
6. "Is a nicotine vaccine a magic bullet for smoking cessation" Law Center U of Houston, Aug 17, 2000
7. "Clinical trial to begin on nicotine-addiction vaccine!" Itasca Psychiatric Service, Apr. 2001
8. "Nabi-NicVAX(TM) Data Presented At The Society" AHC News, Apr, 1999
9. "Nabi receives U.S. patent covering NABI® NICVAX™" Nabi Press Release, May 11, 2001
10. "New vaccine sends nicotine's pleasurable effects up in smoke" CBS News, Oct 23, 2001
11. "Nabi Pharmaceuticals begins human tesing of novel vaccine to fight nicotine addiction" Science Blog, June, 2002
11. "Nicotine vaccine; The buzz stops here" Smoking cessation in About
12. "Key facts of nicotine addiction and NicVAXTM" Nabi, June 13, 2003
13. "Encouraging results from NicVAX Phase I/II clinical trial in smokers and non-smokers" Biospace, Feb 25, 2004 
14. "Japanese smokers pursue the government in anti-tobacco case"(日本でもタバコ訴訟) ABC online June 8, 2004 
15. "禁煙のためのニコチンワクチン有望" 日経ヘルス 2004年10月5日

  テレビニュースリポート(抜粋)

CBS (national) evening news, 5:30 PM, Dec.17, '99
Ch4 (local in MPLS): Evening news, 5, 6 and 10 PM, Dec 17, '99  
Ch5 (local in MPLS): Evening news, 5, 6 and 10 PM, Dec 17, '99
Ch9 (local in MPLS): Evening news, 9 and 10 PM, Dec. 17, '99
KARE (local in MPLS): Evening news, 5, 6 and 10 PM, Dec 17, '99
ABC(national) evening news, 5:30 PM, Aug 7, '00


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